SCHEMBL5050464

SCHEMBL5050464

CCOc1cccc(N)c1OCC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
L3MBTL1 Q9Y468 5/20 0.47
HSD17B10 Q99714 3/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
GRK6 P43250 1/20 0.42
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10353929 0.88 ALDH1A1 (0.57) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
SCHEMBL3426858 0.88 ALDH1A1 (0.62) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
SCHEMBL6943999 0.87 ALDH1A1 (0.58) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
SCHEMBL2068454 0.84 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPTKDM4EMEN1
SCHEMBL1838872 0.81 ALDH1A1 (0.69) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
SCHEMBL6675123 0.81 ALDH1A1 (0.53) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
SCHEMBL29466998 0.80 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
SCHEMBL15704 0.80 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10MAPTKDM4E
Potassium Ion SCHEMBL28222970 0.80 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTKDM4EMEN1
Methyl Alcohol SCHEMBL28171303 0.80 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
EP-4731689-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE Covestro Deutschland AG (DE) 2026-04-29 EP disclosed
EP-4448605-B1 PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
EP-4200353-B1 METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
EP-4200352-B1 METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
EP-4200351-B1 METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-11-19 EP disclosed
US-12378348-B2 Method for the production of a thermoplastic polyoxazolidinone COVESTRO DEUTSCHLAND AG (DE) 2025-08-05 US disclosed
US-20250043061-A1 PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2025-02-06 US disclosed
WO-2024260858-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE COVESTRO DEUTSCHLAND AG (DE) 2024-12-26 WO disclosed
EP-4448605-A1 PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE Covestro Deutschland AG (DE) 2024-10-23 EP disclosed
US-4601725-A POLYETHER DYES MILLIKEN RESEARCH CORPORATION (US) 1986-07-22 US disclosed
EP-0063269-B1 PROCESS FOR PREPARING AMINO-ARYLSULPHONIC ACIDS BAYER AG (DE) 1985-09-11 EP disclosed
EP-0063271-B1 PROCESS FOR PREPARING AROMATIC AMINO-SULPHONIC ACIDS BAYER AG (DE) 1984-12-12 EP disclosed
EP-0119428-A2 Biscarboxamides for treating diseases, and process for their preparation BAYER AG (DE) 1984-09-26 EP disclosed
US-4447368-A Process for the preparation of aminoarylsulphonic acids in sulfolene solvent SIEMENS-ALLIS, INC. (US) 1984-05-08 US disclosed
US-4435336-A FROM ARYLAMINE AND SULFONIC ACID, OR CORRESPONDING ARYLAMMONIUM HY BAYER AKTIENGESELLSCHAFT (DE) 1984-03-06 US disclosed
EP-0063271-A1 Process for preparing aromatic amino-sulphonic acids BAYER AG (DE) 1982-10-27 EP disclosed
EP-0063269-A1 Process for preparing amino-arylsulphonic acids BAYER AG (DE) 1982-10-27 EP disclosed
US-4164511-A Manufacture of N-arylglycinonitriles BASF AKTIENGESELLSCHAFT (DE) 1979-08-14 US disclosed
US-4024125-A Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed