Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5577065 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL9388102 | 0.82 | CYP3A4 (0.33) | — | |
| Bromide SCHEMBL225300 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL73165 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL5030190 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1586512 | 0.82 | — | — | |
| Bromide SCHEMBL3131407 | 0.67 | — | — | |
| Bromide SCHEMBL2229498 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8424965 | 0.67 | — | — | |
| Bromide SCHEMBL726124 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304309-B2 | Radiation detectors | SUHAMI AVRAHAM | 2007-12-04 | — | — | US | claimed |
| US-20060202125-A1 | Radiation detectors | SUHAMI AVRAHAM | 2006-09-14 | — | — | US | claimed |
| CN-102230215-B | Preparation method of cerium-doped lanthanum chlorobromide scintillating crystal | UNIV JILIANG CHINA | 2015-05-13 | — | — | CN | disclosed |
| CN-102230215-B | Preparation method of cerium-doped lanthanum chlorobromide scintillating crystal | UNIV JILIANG CHINA | 2015-05-13 | — | — | CN | disclosed |
| CN-102230215-A | Preparation method of cerium-doped lanthanum chlorobromide scintillating crystal | UNIV JILIANG CHINA | 2011-11-02 | — | — | CN | disclosed |
| CN-102230215-A | Preparation method of cerium-doped lanthanum chlorobromide scintillating crystal | UNIV JILIANG CHINA | 2011-11-02 | — | — | CN | disclosed |
| US-20080185074-A1 | Preparation of compositions by melt spinning | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-08-07 | — | — | US | disclosed |
| US-7304309-B2 | Radiation detectors | SUHAMI AVRAHAM | 2007-12-04 | — | — | US | disclosed |
| US-20060202125-A1 | Radiation detectors | SUHAMI AVRAHAM | 2006-09-14 | — | — | US | disclosed |
| US-4780611-A | CERIUM ACTIVATED RARE EARTH HALIDE COMPLEX PHOSPHOR, STIMULATING WITH LASER BEAM | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-25 | — | — | US | disclosed |
| US-4761347-A | CERIUM ACTIVATED RARE EARTH COMPLEX HALIDE PHOSPHOR | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |