Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | PPP3CA | Q08209 | 1/20 | 0.33 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5030190 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL73165 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL14691151 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11803063 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8424971 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8424965 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL9741054 | 0.82 | — | — | |
| Bromide SCHEMBL5050692 | 0.82 | — | — | |
| Water SCHEMBL73305 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL9740106 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994012194-A1 | COMPOSITIONS FOR TREATING CORNS, CALLUSES AND WARTS COMPRISING SALICYLIC ACID AND LANTHANIDE | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1994-06-09 | — | — | WO | claimed |
| WO-1994012194-A1 | COMPOSITIONS FOR TREATING CORNS, CALLUSES AND WARTS COMPRISING SALICYLIC ACID AND LANTHANIDE | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1994-06-09 | — | — | WO | disclosed |