Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474970 | 0.83 | MAPT (0.59) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| SCHEMBL5052519 | 0.82 | TDP1 (0.51) | MAPTSMN1; SMN2LIN28ATDP1CHRNA7 | |
| SCHEMBL13955267 | 0.82 | MAPT (0.47) | MAPTSMN1; SMN2LIN28ATDP1CHRNA7 | |
| SCHEMBL5050033 | 0.79 | CHRNA7 (0.49) | MAPTSMN1; SMN2LIN28ATDP1CHRNA7 | |
| SCHEMBL13936660 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2LIN28ATDP1CHRNA7 | |
| Zinc Ion SCHEMBL30268708 | 0.79 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| SCHEMBL138261 | 0.77 | SMN1; SMN2 (0.83) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| Hydrochloric Acid SCHEMBL9905725 | 0.75 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| SCHEMBL31533189 | 0.75 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| SCHEMBL14357958 | 0.75 | MAPT (0.79) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-20040224420-A1 | Sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-11 | — | — | US | disclosed |