Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.63 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889830 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL8389930 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL28786185 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL8039895 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL6047707 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL10145513 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL17942985 | 1.00 | KDM4A (0.63) | KDM4AKDM4CADRA1ATSHRLMNA | |
| Hydrochloric Acid SCHEMBL3484697 | 0.98 | KDM4A (0.67) | KDM4AKDM4CADRA1ATSHRLMNA | |
| Hydrochloric Acid SCHEMBL4405208 | 0.98 | KDM4A (0.67) | KDM4AKDM4CADRA1ATSHRLMNA | |
| SCHEMBL693740 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205244-B | Thiazolo-ring compound, preparation method, intermediate and application thereof | 上海科技大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-113387938-A | Substituted pyrimidine compound, preparation method, intermediate and application thereof | 上海科技大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-111205244-A | Thiazolocyclic compound, preparation method, intermediate and application thereof | 上海科技大学 | 2020-05-29 | — | — | CN | disclosed |
| US-10065133-B2 | Separation material comprising phosphoryl choline derivatives | PENTRACOR GMBH (DE) | 2018-09-04 | — | — | US | disclosed |
| EP-3041852-B1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | PENTRACOR GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-20170120163-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | PENTRACOR GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20170097567-A1 | METHOD FOR PRODUCING POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20160229940-A1 | POLYMER, RESIST COMPOSITION, AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| EP-3041852-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | Pentracor GmbH (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-9272242-B2 | High cyclic capacity amines for high efficiency CO2 scrubbing processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-03-01 | — | — | US | disclosed |
| US-8524727-B2 | Pyrimidine compound | ASTELLAS PHARMA INC. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-8524727-B2 | Pyrimidine compound | ASTELLAS PHARMA INC. (JP) | 2013-09-03 | — | — | US | disclosed |
| EP-2415765-A1 | PYRIMIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20110053912-A1 | PYRIMIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110053912-A1 | PYRIMIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-03-03 | — | — | US | disclosed |
| WO-2010113834-A1 | PYRIMIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-07 | — | — | WO | disclosed |
| US-20080125440-A1 | TYROSINE KINASE INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. | 2008-05-29 | — | — | US | disclosed |
| US-7179819-B2 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170120163-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | CHKA, PHOSPHO1, C3AR1 | KDM4A 2414/4885KDM4C 1804/4885ADRA1A 1606/4885 |
| US-20110053912-A1 | PYRIMIDINE COMPOUND | CNR2, CNR1, P2RY2 | KDM4A 2786/4885KDM4C 2644/4885ADRA1A 530/4885 |
| US-10065133-B2 | Separation material comprising phosphoryl choline derivatives | CHKA, PHOSPHO1, CHKB | KDM4A 2261/4885KDM4C 1538/4885ADRA1A 1938/4885 |
| US-20080125440-A1 | TYROSINE KINASE INHIBITORS CONTAINING A ZINC BINDING MOIETY | LCK, ABL1, SRC | KDM4A 397/4885KDM4C 604/4885ADRA1A 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.