⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1065087 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL10145513 | 0.97 | KDM4A (0.63) | — | |
| Water SCHEMBL3641025 | 0.97 | KDM4A (0.58) | — | |
| SCHEMBL5050892 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL8389930 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL6047707 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL17942985 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL889830 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL8039895 | 0.97 | KDM4A (0.63) | — | |
| SCHEMBL28786185 | 0.97 | KDM4A (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129125-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2025-04-24 | — | — | US | claimed |
| EP-4168121-A2 | MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| CN-115702026-A | Macrocyclic compounds and methods of use thereof | 基因泰克公司 | 2023-02-14 | — | — | CN | claimed |
| US-20220106361-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2022-04-07 | — | — | US | claimed |
| US-10357497-B2 | Pro-drugs of riluzole and their method of use for the treatment of amyotrophic lateral sclerosis | Biohaven Pharmaceutical Holding Company Limited (US) | 2019-07-23 | — | — | US | claimed |
| US-9725427-B2 | Prodrugs of riluzole and their method of use | Biohaven Pharmaceutical Holding Company Limited (US) | 2017-08-08 | — | — | US | claimed |
| US-20150148329-A1 | PRO-DRUGS OF RILUZOLE AND THEIR METHOD OF USE FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | BEETLEJUICE SA LLC, AS PURCHASER AGENT | 2015-05-28 | — | — | US | claimed |
| US-20150045401-A1 | PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE | BEETLEJUICE SA LLC, AS PURCHASER AGENT | 2015-02-12 | — | — | US | claimed |
| WO-2013192610-A2 | PRO-DRUGS OF RILUZOLE AND THEIR METHOD OF USE FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2013-12-27 | — | — | WO | claimed |
| WO-2013138753-A1 | PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2013-09-19 | — | — | WO | claimed |
| EP-0626374-B1 | A diaminostilbene series compound and a method for forming an image using the same | FUJI PHOTO FILM CO LTD (JP) | 2002-08-07 | — | — | EP | claimed |
| US-5395742-A | IMAGEWISE EXPOSURE OF A PHOTOGRAPHIC MATERIAL TO LIGHT | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-07 | — | — | US | claimed |
| EP-0626374-A2 | A diaminostilbene series compound and a method for forming an image using the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-30 | — | — | EP | claimed |
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4702044-A1 | GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER | 3B Pharmaceuticals GmbH (DE) | 2026-03-04 | — | — | EP | disclosed |
| US-20250296971-A1 | GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2025-09-25 | — | — | US | disclosed |
| EP-0626374-A2 | A diaminostilbene series compound and a method for forming an image using the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |
| CN-1016869-B | Process for preparing 6, 7-diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KK (JP) | 1992-06-03 | — | — | CN | disclosed |
| EP-0356041-A2 | Non-linear optical element | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |
| CN-1030583-A | Preparation 6,7-diacyl-7-takes off the novel method of acetyl forskrine derivant | NIPPON KAYAKU KK (JP) | 1989-01-25 | — | — | CN | disclosed |