Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 15/20 | 0.78 |
| ▸ | MEN1 | O00255 | 12/20 | 0.78 |
| ▸ | POLB | P06746 | 5/20 | 0.69 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | XBP1 | P17861 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.69 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | PTPN12 | Q05209 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.62 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.62 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051688 | 1.00 | KMT2A (0.78) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL12692505 | 0.91 | KMT2A (0.92) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL10088087 | 0.91 | KMT2A (0.76) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL12692426 | 0.88 | MEN1 (1.00) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL12008780 | 0.86 | KMT2A (0.83) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL5049214 | 0.83 | KMT2A (0.73) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL5049215 | 0.83 | KMT2A (0.73) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL12008621 | 0.82 | KMT2A (0.75) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL12008563 | 0.82 | GPR35 (0.76) | KMT2AMEN1POLBGPR35MAPT | |
| SCHEMBL12008794 | 0.80 | KMT2A (0.84) | KMT2AMEN1POLBGPR35MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393869-B2 | Methods of using thiazolidine derivatives to treat cancer or inflammation | QLT INC. (CA) | 2008-07-01 | — | — | US | claimed |