SCHEMBL5051998

SCHEMBL5051998

O=c1ccn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)F)O2)c(=O)[nH]1

nearest known ligand 0.76

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.76
P2RY2 P41231 1/20 0.56
P2RY4 P51582 1/20 0.56
P2RY6 Q15077 1/20 0.56
TYMS P04818 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyuridine Monophosphate SCHEMBL8200 0.92 DUT (0.77) DUTTYMS
Deoxyuridine Monophosphate SCHEMBL21941035 0.92 DUT (0.77) DUTTYMS
Deoxyuridine Monophosphate SCHEMBL25024676 0.92 DUT (0.77) DUTTYMS
Deoxyuridine Monophosphate SCHEMBL888328 0.92 DUT (0.77) DUTTYMS
SCHEMBL4263613 0.89 DUT (0.73) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL5565558 0.89 DUT (0.73) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL21626116 0.88 DUT (0.78) DUTP2RY2P2RY4P2RY6
SCHEMBL21067966 0.88 DUT (0.78) DUTP2RY2P2RY4P2RY6
SCHEMBL22198883 0.88 DUT (0.75) DUTP2RY2P2RY4P2RY6
SCHEMBL156694 0.88 DUT (0.78) DUTP2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040102409-A1 Medicament for locally treating or preventing a chemotherapy-induced mucositis and other side effects resulting from chemotherapy NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2004-05-27 US claimed
EP-1414482-A2 MEDICAMENT FOR LOCALLY TREATING OR PREVENTING A CHEMOTHERAPY-INDUCED MUCOSITIS AND OTHER SIDE EFFECTS RESULTING FROM CHEMOTHERAPY Geurtsen, Werner (DE) 2004-05-06 EP claimed
WO-2002047709-A2 RESISTANT THYMIDYLATE SYNTHASE MUTANTS FOR LOCALLY TREATING A CHEMOTHERAPY-INDUCED MUCOSITIS AND OTHER SIDE EFFECTS ASSOCIATED WITH CHEMOTHERAPY GEURTSEN WERNER (DE) 2002-06-20 WO claimed
US-5534519-A 5,10,-methylene-tetrahydrofolate as a modulator of a chemotherapeutic agent UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1996-07-09 US claimed
WO-1991017660-A1 5,10-METHYLENE-TETRAHYDROFOLATE AS A MODULATOR OF A CHEMOTHERAPEUTIC AGENT SPEARS COLIN P (US) 1991-11-28 WO claimed
EP-4735116-A2 ANTI-TRAILR2 ANTIGEN-BINDING PROTEINS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2026-05-06 EP disclosed
EP-4648792-A2 ANTI-TNFR2 ANTIGEN-BINDING PROTEINS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-11-19 EP disclosed
WO-2025217240-A1 ANTI-TNFR2 ANTIGEN-BINDING PROTEINS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-10-16 WO disclosed
CN-120129702-A RNA compositions targeting claudin-18.2 生物技术公司 2025-06-10 CN disclosed
US-12325859-B2 Microbial approach for the production of long chain compounds UT-BATTELLE, LLC (US) 2025-06-10 US disclosed
WO-2025080751-A2 ANTI-CDH17 ANTIGEN-BINDING PROTEINS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-04-17 WO disclosed
WO-2025006846-A2 ANTI-TRAILR2 ANTIGEN-BINDING PROTEINS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-01-02 WO disclosed
US-6258360-B1 BENZOATE CONJUGATES; ANTITUMOR AGENTS IGEN INTERNATIONAL, INC. 2001-07-10 US disclosed
WO-2001019320-A2 PHOSPHOLIPID PRODRUGS OF ANTI-PROLIFERATIVE DRUGS D-PHARM LIMITED (IL) 2001-03-22 WO disclosed
EP-0746336-A1 PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS IGEN, INC. (US) 1996-12-11 EP disclosed
EP-0746336-A4 PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS IGEN INC (US) 1996-07-26 EP disclosed
US-5534519-A 5,10,-methylene-tetrahydrofolate as a modulator of a chemotherapeutic agent UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1996-07-09 US disclosed
US-5376658-A 5,10-methylene-tetrahydrofolate as a modulator of a chemotherapeutic agent UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1994-12-27 US disclosed
WO-1993002703-A1 PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS IGEN, INC. (US) 1993-02-18 WO disclosed
WO-1991017660-A1 5,10-METHYLENE-TETRAHYDROFOLATE AS A MODULATOR OF A CHEMOTHERAPEUTIC AGENT SPEARS COLIN P (US) 1991-11-28 WO disclosed