SCHEMBL5052008

SCHEMBL5052008

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nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 1/20 0.44
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
KDM4E B2RXH2 2/20 0.34
OR51E2 Q9H255 1/20 0.31
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5052009 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL5058650 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL29620322 0.82 LMNA (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL21014430 0.82 LMNA (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL769397 0.77 PDE4A (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL2933537 0.77 PDE4A (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL13430947 0.77 PDE4A (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL19327387 0.77 PDE4A (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL18105811 0.77 PDE4A (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
Adonitol SCHEMBL29012527 0.75 LMNA (0.62) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1952919-A2 Magnetic nanoparticles and aqueous colloid composition containing the same Fujifilm Corporation (JP) 2008-08-06 EP disclosed