Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056800 | 1.00 | ACE (0.59) | ACEALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL5054637 | 1.00 | ACE (0.59) | ACEALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL1854231 | 0.85 | ACE (0.77) | ACEALDH1A1MAPTKMT2AFOLH1 | |
| SCHEMBL8155389 | 0.85 | ALDH1A1 (0.77) | ACEALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL2439884 | 0.85 | ALDH1A1 (0.77) | ACEALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL11683116 | 0.82 | ALDH1A1 (0.62) | ACEALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL28966701 | 0.82 | ALDH1A1 (0.71) | ACEALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL441981 | 0.82 | — | — | |
| SCHEMBL7460319 | 0.82 | — | — | |
| SCHEMBL18506612 | 0.80 | ALDH1A1 (0.59) | ACEALDH1A1LMNASLC15A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7404928-B2 | Thiol terminated monodisperse ethylene oxide oligomer capped gold nanoclusters | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-07-29 | — | — | US | disclosed |
| US-20040018633-A1 | Thiol terminated monodisperse ethylene oxide oligomer capped gold nanoclusters | NAVY, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE, THE | 2004-01-29 | — | — | US | disclosed |