SCHEMBL5052771

SCHEMBL5052771

O=c1ccn([C@]2(Br)O[C@H](CO)[C@@H](O)[C@H]2F)c(=O)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.46
SLC28A2 O43868 1/20 0.46
SLC29A1 Q99808 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.46
P2RY14 Q15391 10/20 0.41
P2RY6 Q15077 3/20 0.38
P2RY2 P41231 3/20 0.38
P2RY4 P51582 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5052765 1.00 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL154357 0.89 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL425422 0.84 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL15255033 0.83 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL17479413 0.83 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL27552226 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30103795 0.81 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30450897 0.80 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL98410 0.79 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL30514301 0.78 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206805-A1 Combination Therapy with Gold Controlled Transgenes CHIMERA BIOENGINEERING, INC. (US) 2025-06-26 US disclosed
CN-111989108-B Coordinating gene expression using RNA destabilizing elements 嵌合体生物工程公司 2024-07-16 CN disclosed
EP-4342978-A2 GOLD OPTIMIZED CAR T-CELLS Chimera Bioengineering Inc. (US) 2024-03-27 EP disclosed
EP-3858365-B1 GOLD OPTIMIZED CAR T-CELLS CHIMERA BIOENGINEERING INC (US) 2024-01-31 EP disclosed
EP-4232051-A1 MERCURY CONTROLLED GENE EXPRESSION CHIMERA BIOENGINEERING, INC. (US) 2023-08-30 EP disclosed
US-11648277-B2 Combination therapy with gold controlled transgenes CHIMERA BIOENGINEERING, INC. (US) 2023-05-16 US disclosed
US-11572566-B2 Gold optimized CAR t-cells CHIMERA BIOENGINEERING, INC. (US) 2023-02-07 US disclosed
US-20230028899-A1 Mercury Controlled Gene Expression CHIMERA BIOENGINEERING, INC. (US) 2023-01-26 US disclosed
US-11535853-B2 Gold optimized CAR T-cells CHIMERA BIOENGINEERING, INC. (US) 2022-12-27 US disclosed
US-11497774-B2 Coordinating gene expression using RNA destabilizing elements CHIMERA BIOENGINEERING, INC. (US) 2022-11-15 US disclosed
US-20220228156-A1 Gold Optimized CAR T-cells CHIMERA BIOENGINEERING, INC. (US) 2022-07-21 US disclosed
US-20220226381-A1 Coordinating Gene Expression Using RNA Destabilizing Elements CHIMERA BIOENGINEERING, INC. (US) 2022-07-21 US disclosed
US-20220204977-A1 Gold Optimized CAR T-cells CHIMERA BIOENGINEERING, INC. (US) 2022-06-30 US disclosed
EP-4013431-A1 COMBINATION THERAPY WITH GOLD CONTROLLED TRANSGENES CHIMERA BIOENGINEERING, INC. (US) 2022-06-22 EP disclosed
US-20220186233-A1 Gold Optimized CAR T-cells CHIMERA BIOENGINEERING, INC. (US) 2022-06-16 US disclosed
WO-2022086875-A1 MERCURY CONTROLLED GENE EXPRESSION CHIMERA BIOENGINEERING, INC. (US) 2022-04-28 WO disclosed
US-11311577-B2 Coordinating gene expression using RNA destabilizing elements CHIMERA BIOENGINEERING, INC. (US) 2022-04-26 US disclosed
US-20080181847-A1 Targeted Imaging and/or Therapy Using the Staudinger Ligation KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-07-31 US disclosed
EP-1799273-A2 USE OF THE STAUDINGER LIGATION IN IMAGING AND THERAPY END KITS FOR IMAGING AND THERAPY Koninklijke Philips Electronics N.V. (NL) 2007-06-27 EP disclosed
WO-2006038185-A2 USE OF THE STAUDINGER LIGATION IN IMAGING AND THERAPY END KITS FOR IMAGING AND THERAPY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181847-A1 Targeted Imaging and/or Therapy Using the Staudinger Ligation BTD, HLCS, BOLA2; BOLA2B SLC28A1 4258/4885SLC28A2 4092/4885SLC29A1 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.