SCHEMBL5054

SCHEMBL5054

Fc1ccccc1CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765100 1.00
SCHEMBL20465742 1.00
SCHEMBL4441044 0.97 TAAR1 (0.52)
SCHEMBL1538044 0.97 TAAR1 (0.52)
Water SCHEMBL450787 0.97 TAAR1 (0.52)
Benzene SCHEMBL28870609 0.97 TAAR1 (0.52)
Benzyl Bromide SCHEMBL6043969 0.89 ALDH1A1 (0.61)
Bicarbonate SCHEMBL16454532 0.85 ALDH1A1 (0.43)
SCHEMBL7364761 0.85 CYP3A4 (0.48)
Bicarbonate SCHEMBL16454533 0.85 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4323 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
CN-116375643-B Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2025-04-01 CN claimed
CN-119569727-A Preparation method of key intermediate of vitamin Li Xigu 合肥菁科生物科技有限公司 2025-03-07 CN claimed
CN-119569808-A Method for modifying C-21 position structure of fusidic acid 浙江工业大学 2025-03-07 CN claimed
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-115536585-B Iminostilbene derivative and preparation method thereof 中国医学科学院药用植物研究所 2024-04-30 CN claimed
CN-117924295-A Furimazine derivative and preparation method and application thereof 广州博鹭腾生物科技有限公司 2024-04-26 CN claimed
CN-114773330-B Butylphthalide-oxa/thiadiazole compound and preparation method and application thereof 贵州医科大学 2024-03-15 CN claimed
CN-117126099-A 3-benzyloxy methyl indole-2-carboxylic acid derivative and preparation method and application thereof 贵州医科大学 2023-11-28 CN claimed
US-11773109-B2 Composition for hardening soft tissue THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION 2023-10-03 US claimed
CN-102030761-B Prasugrel midbody and preparation method thereof ZHEJIANG PULUO JIAYUAN PHARMACEUTICAL CO LTD 2012-10-10 CN claimed
CN-102030761-A Prasugrel midbody and preparation method thereof ZHEJIANG PULUO JIAYUAN PHARMACEUTICAL CO LTD 2011-04-27 CN claimed
CN-101823952-A Method for preparing 2,4,5-trifluorophenylacetic acid UNIV DALIAN TECH 2010-09-08 CN claimed
CN-101805241-A New method for preparing fluoro-substituted indene compound CHANGZHOU SHENGYONG PHOTOELECTRICITY MATERIALS CO LTD 2010-08-18 CN claimed
WO-2010070677-A2 A PROCESS FOR THE PREPARATION OF PRASUGREL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF GLENMARK GENERICS LIMITED (IN) 2010-06-24 WO claimed
CN-101735241-A Prasugrel intermediate and preparation method thereof ZHEJIANG APELOA HOME PHARMACEU 2010-06-16 CN claimed
WO-2009066326-A2 IMPROVED PROCESS FOR THE PREPARATION OF PRASUGREL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2009-05-28 WO claimed
CN-101346334-A Tetrafluorotoluene compound, method for producing same and use thereof SUMITOMO CHEMICAL CO (JP) 2009-01-14 CN claimed
US-5565602-A REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US claimed
EP-0045430-A1 Process for the bromination in the alpha-position of possibly substituted fluortoluenes and mixtures of possibly substituted fluortoluenes having a different number of bromine atoms in the alpha-position BAYER AG (DE) 1982-02-10 EP claimed