Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058845 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL6382754 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL900095 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL75505 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL5431682 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL24004713 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL16898630 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL6161898 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL21705290 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL6159754 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | claimed |
| US-11833142-B2 | 3-(5-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2023-12-05 | — | — | US | disclosed |
| US-9725550-B2 | Block copolymer, method of forming the same, and method of forming pattern | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9725550-B2 | Block copolymer, method of forming the same, and method of forming pattern | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-20160090435-A1 | BLOCK COPOLYMER, METHOD OF FORMING THE SAME, AND METHOD OF FORMING PATTERN | SAMSUNG DISPLAY CO LTD (KR) | 2016-03-31 | — | — | US | disclosed |
| US-20160090435-A1 | BLOCK COPOLYMER, METHOD OF FORMING THE SAME, AND METHOD OF FORMING PATTERN | SAMSUNG DISPLAY CO LTD (KR) | 2016-03-31 | — | — | US | disclosed |
| EP-2177598-B1 | The use of isomers of bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, ethyl ester in perfume compositions and perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2011-07-13 | — | — | EP | disclosed |
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | disclosed |
| EP-0912170-A4 | HIV PROTEASE INHIBITORS USEFUL FOR THE TREATMENT OF AIDS | MERCK & CO INC (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0912170-A1 | HIV PROTEASE INHIBITORS USEFUL FOR THE TREATMENT OF AIDS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997040825-A1 | HIV PROTEASE INHIBITORS USEFUL FOR THE TREATMENT OF AIDS | MERCK & CO., INC. (US) | 1997-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833142-B2 | 3-(5-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | RXFP3, RXFP1, NPY2R | KDM4E 2398/4885LMNA 1606/4885TDP1 192/4885 |
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | NT5E, NT5C2, CPN1 | KDM4E 3956/4885LMNA 2235/4885TDP1 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.