Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054199 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL5058845 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL6382754 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL75505 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL5431682 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL24004713 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL16898630 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL6161898 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL21705290 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 | |
| SCHEMBL6159754 | 1.00 | KDM4E (0.61) | KDM4ELMNATDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437426-B | Brush copolymer and preparation method thereof | 苏州大学 | 2022-04-26 | — | — | CN | claimed |
| US-20210002469-A1 | TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-01-07 | — | — | US | claimed |
| WO-2019183140-A1 | TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2019-09-26 | — | — | WO | claimed |
| EP-2847245-B1 | METHOD FOR THE MANUFACTURE OF COATED ARTICLES AND COATED ARTICLES | MERCENE LABS AB (SE) | 2019-01-02 | — | — | EP | claimed |
| US-9862857-B2 | Method and formulations for the manufacture of coated articles and composites | MERCENE LABS AB (SE) | 2018-01-09 | — | — | US | claimed |
| US-20160369127-A1 | METHOD AND FORMULATIONS FOR THE MANUFACTURE OF COATED ARTICLES AND COMPOSITES | MERCENE LABS AB (SE) | 2016-12-22 | — | — | US | claimed |
| US-9523019-B2 | Method and formulations for the manufacture of coated articles and composites | MERCENE LABS AB (SE) | 2016-12-20 | — | — | US | claimed |
| EP-2622002-B1 | METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS | MERCENE LABS AB (SE) | 2016-02-24 | — | — | EP | claimed |
| US-20150118456-A1 | METHOD AND FORMULATIONS FOR THE MANUFACTURE OF COATED ARTICLES AND COMPOSITES | MERCENE LABS AB (SE) | 2015-04-30 | — | — | US | claimed |
| EP-2847245-A2 | METHOD FOR THE MANUFACTURE OF COATED ARTICLES AND COATED ARTICLES | Mercene Labs AB (SE) | 2015-03-18 | — | — | EP | claimed |
| US-20130331528-A1 | METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS | MERCENE LABS AB (SE) | 2013-12-12 | — | — | US | claimed |
| WO-2013167576-A2 | METHOD AND FORMULATIONS FOR THE MANUFACTURE OF COATED ARTICLES AND COMPOSITES | MERCENE LABS AB (SE) | 2013-11-14 | — | — | WO | claimed |
| EP-2622002-A1 | METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS | Mercene Labs AB (SE) | 2013-08-07 | — | — | EP | claimed |
| US-20130123381-A1 | Novel Resin Systems for Dental Restorative Materials and Methods Using Same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-05-16 | — | — | US | claimed |
| US-20120256338-A1 | NEW RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-10-11 | — | — | US | claimed |
| US-8192673-B2 | Resin systems for dental restorative materials | UNIVERSITY OF KANSAS (US) | 2012-06-05 | — | — | US | claimed |
| WO-2012042059-A1 | METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS | CARLBORG CARL FREDRIK (SE) | 2012-04-05 | — | — | WO | claimed |
| WO-2010114760-A1 | NEW RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2010-10-07 | — | — | WO | claimed |
| US-20090270528-A1 | RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2009-10-29 | — | — | US | claimed |
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002469-A1 | TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE | CRH, CNKSR1, RAD51 | KDM4E 570/4885LMNA 2108/4885TDP1 999/4885 |
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | NT5E, NT5C2, CPN1 | KDM4E 3956/4885LMNA 2235/4885TDP1 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.