Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455142 | 0.87 | PIM1 (0.35) | PIM1AKT2MAPT | |
| SCHEMBL1454273 | 0.87 | PIM1 (0.38) | PIM1AKT2MAPK14 | |
| SCHEMBL1454998 | 0.86 | PIM1 (0.38) | PIM1AKT2 | |
| SCHEMBL1455491 | 0.85 | PIM1 (0.37) | PIM1AKT2MAPT | |
| SCHEMBL1456231 | 0.85 | PIM1 (0.36) | PIM1AKT2 | |
| SCHEMBL1454418 | 0.85 | PIM1 (0.39) | PIM1AKT2MAPK14 | |
| SCHEMBL1455220 | 0.85 | PIM1 (0.36) | PIM1AKT2HPGDMAPT | |
| SCHEMBL1455263 | 0.84 | PIM1 (0.35) | PIM1AKT2MAPTMAPK14 | |
| SCHEMBL1455352 | 0.84 | PIM1 (0.37) | PIM1AKT2 | |
| SCHEMBL1455126 | 0.83 | HPGDS (0.35) | PIM1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |