Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27640442 | 0.88 | NR3C1 (0.32) | IDO1AGXTNR3C1PGRNR3C2 | |
| SCHEMBL2059029 | 0.77 | IDO1 (0.31) | IDO1 | |
| SCHEMBL500057 | 0.76 | IDO1 (0.37) | IDO1AGXTMAOB | |
| SCHEMBL25078628 | 0.74 | MAPT (0.37) | IDO1AGXTMAOB | |
| SCHEMBL10213864 | 0.73 | CXCR2 (0.36) | IDO1AGXTMAOBNR3C1PGR | |
| SCHEMBL500146 | 0.72 | NR3C1 (0.34) | IDO1AGXTNR3C1PGRNR3C2 | |
| SCHEMBL15186177 | 0.72 | IDO1 (0.34) | IDO1AGXTPOLBL3MBTL1 | |
| SCHEMBL27640448 | 0.72 | IDO1 (0.33) | IDO1 | |
| SCHEMBL10213860 | 0.71 | NR3C1 (0.31) | IDO1AGXTNR3C1PGRNR3C2 | |
| SCHEMBL14470725 | 0.71 | NR3C1 (0.31) | IDO1AGXTNR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829521-B | Hydrolysis resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS INC | 2011-01-26 | — | — | CN | disclosed |
| EP-1976536-A2 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| CN-1829521-A | Hydrolysis resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS INC (US) | 2006-09-06 | — | — | CN | disclosed |