Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201702 | 1.00 | ALDH1A1 (0.70) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8915608 | 0.98 | ALDH1A1 (0.68) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Bromide SCHEMBL8916350 | 0.98 | ALDH1A1 (0.68) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Iodide SCHEMBL8916427 | 0.98 | ALDH1A1 (0.68) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| SCHEMBL29566955 | 0.98 | ALDH1A1 (0.68) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Benzene SCHEMBL27399226 | 0.96 | ALDH1A1 (0.71) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Oxalic Acid SCHEMBL8915851 | 0.95 | ALDH1A1 (0.69) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Phosphoric Acid SCHEMBL8915701 | 0.93 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Sulfuric Acid SCHEMBL7456727 | 0.93 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ENPP2KDM4EHPGD | |
| Acetic Acid SCHEMBL8914629 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HSD17B10ENPP2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4376818-B1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2025-06-18 | — | — | EP | claimed |
| EP-3472149-B1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | Orion Ophthalmology LLC (US) | 2023-08-30 | — | — | EP | claimed |
| CN-116057049-A | Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | claimed |
| EP-3541376-B1 | INDOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME LLC (US) | 2023-04-19 | — | — | EP | claimed |
| WO-2023056236-A1 | SEEDLING GERMINATION AND GROWTH CONDITIONS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2023-04-06 | — | — | WO | claimed |
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | claimed |
| EP-4103278-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2022-12-21 | — | — | EP | claimed |
| EP-3802534-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS AS STING ACTIVATORS | Incyte Corporation (US) | 2021-04-14 | — | — | EP | claimed |
| EP-3541376-A1 | INDOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | Merck Sharp & Dohme Corp. (US) | 2019-09-25 | — | — | EP | claimed |
| CN-109963561-A | Indole derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2 | 默沙东公司 | 2019-07-02 | — | — | CN | claimed |
| WO-2004071507-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-08-26 | — | — | WO | claimed |
| JP-2003500480-A | — | — | 2003-01-07 | — | — | JP | claimed |
| EP-1196397-A1 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND THEIR USE FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES | NPS PHARMACEUTICALS, INC. (US) | 2002-04-17 | — | — | EP | claimed |
| CN-1342457-A | Method for preventing vomit and sexual disorder using tetrahydrobenzo [cd] indole-6-formylamine compound | LILLY CO ELI (US) | 2002-04-03 | — | — | CN | claimed |
| CN-1072932-C | Methods for preventing emesis and treating sexual dysfunction using tetrahydrobenzo [ cd ] indole-6-carboxamides | LILLY CO ELI (US) | 2001-10-17 | — | — | CN | claimed |
| CN-1305464-A | Heterocyclic compounds and methods to treat cardiac failure and other disorders | SCIOS INC (US) | 2001-07-25 | — | — | CN | claimed |
| WO-2000073283-A1 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND THEIR USE FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES | NPS PHARMACEUTICALS, INC. (US) | 2000-12-07 | — | — | WO | claimed |
| US-5703112-A | Method of preventing emesis using tetrahydrobenz CD!indole-6-carbonxamides | ELI LILLY AND COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| CN-1100634-A | Methods for preventing emesis and treating sexual dysfunction using tetrahydrobenzo [ cd ] indole-6-carboxamides | LILLY CO ELI (US) | 1995-03-29 | — | — | CN | claimed |
| CN-1046330-A | Tetrahydro benzo [c, d] indole serotonin stimulant | LILLY CO ELI (US) | 1990-10-24 | — | — | CN | claimed |