Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619397 | 0.93 | HPGD (0.57) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8616296 | 0.93 | HPGD (0.57) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8621478 | 0.91 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8615172 | 0.91 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8616688 | 0.91 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9036946 | 0.91 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8613529 | 0.91 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8621032 | 0.91 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8619539 | 0.90 | HPGD (0.59) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3670854 | 0.88 | HPGD (0.51) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080206139-A1 | DELIVERY SYSTEM FOR DIAGNOSTIC AND THERAPEUTIC AGENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-08-28 | — | — | US | disclosed |
| US-20070160658-A1 | Delivery system for diagnostic and therapeutic agents | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-07-12 | — | — | US | disclosed |
| WO-2007048019-A2 | DELIVERY SYSTEM FOR DIAGNOSTIC AND THERAPEUTIC AGENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-04-26 | — | — | WO | disclosed |