SCHEMBL5056320

SCHEMBL5056320

CC(C)(C)OC(=O)NCCCCCCCCCCCOS(C)(=O)=O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
CA1 P00915 10/20 0.57
CA2 P00918 10/20 0.57
CA12 O43570 7/20 0.57
CA9 Q16790 7/20 0.57
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MMP9 P14780 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
ACHE P22303 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6170516 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL21997325 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL26641099 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL7527124 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL1057873 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL23833687 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL691118 0.98 TDP1 (0.58) TDP1CA1CA2CA12CA9
SCHEMBL455207 0.94 TDP1 (0.56) TDP1CA1CA2CA12CA9
SCHEMBL5572140 0.91 TDP1 (0.55) TDP1CA1CA2CA12CA9
SCHEMBL21070840 0.88 TDP1 (0.50) TDP1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392504-A4 SENSOR SURFACES FOR DETECTING ANALYTES AGILENT TECHNOLOGIES INC (US) 2008-03-05 EP disclosed
US-7208322-B2 Sensor surfaces for detecting analytes AGILENT TECHNOLOGIES, INC. (US) 2007-04-24 US disclosed
US-7208322-B2 Sensor surfaces for detecting analytes AGILENT TECHNOLOGIES, INC. (US) 2007-04-24 US disclosed
US-7179659-B2 Detection of preferential particles in sample; obtain sample, incubate with sensor and substrate, monitor and measure response, evaluate for presence of particle AGILENT TECHNOLOGIES, INC. (US) 2007-02-20 US disclosed
US-7179659-B2 Detection of preferential particles in sample; obtain sample, incubate with sensor and substrate, monitor and measure response, evaluate for presence of particle AGILENT TECHNOLOGIES, INC. (US) 2007-02-20 US disclosed
EP-1392504-A1 SENSOR SURFACES FOR DETECTING ANALYTES Prolinx Incorporated (US) 2004-03-03 EP disclosed
US-20030032202-A1 Sensor surfaces for detecting analytes and methods of use PROLINX INCORPORATED (US) 2003-02-13 US disclosed
US-20020192722-A1 Sensor surfaces for detecting analytes PROLINX INCORPORATED (US) 2002-12-19 US disclosed
WO-2002078947-A1 SENSOR SURFACES FOR DETECTING ANALYTES PROLINX INCORPORATED (US) 2002-10-10 WO disclosed