SCHEMBL7527124

SCHEMBL7527124

CC(C)(C)OC(=O)NCCCCCCCCCCCCOS(C)(=O)=O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
CA1 P00915 10/20 0.57
CA2 P00918 10/20 0.57
CA12 O43570 7/20 0.57
CA9 Q16790 7/20 0.57
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MMP9 P14780 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
ACHE P22303 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5056320 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL6170516 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL21997325 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL26641099 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL1057873 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL23833687 1.00 TDP1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL691118 0.98 TDP1 (0.58) TDP1CA1CA2CA12CA9
SCHEMBL455207 0.94 TDP1 (0.56) TDP1CA1CA2CA12CA9
SCHEMBL5572140 0.91 TDP1 (0.55) TDP1CA1CA2CA12CA9
SCHEMBL21070840 0.88 TDP1 (0.50) TDP1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11891558-B2 Solid foam comprising mesogenic ligand-functionalized nanoparticles and methods of making and using the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-02-06 US disclosed
US-11708530-B2 Organic ligands for templatable mesoscale nanocapsules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-25 US disclosed
US-20210179939-A1 Organic Ligands For Templatable Mesoscale Nanocapsules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-06-17 US disclosed
US-20200239781-A1 Solid Foam Comprising Mesogenic Ligand-Functionalized Nanoparticles and Methods of Making and Using the Same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-07-30 US disclosed
WO-2019079507-A1 SOLID FOAM COMPRISING MESOGENIC LIGAND-FUNCTIONALIZED NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-25 WO disclosed
EP-0882716-B1 PYRIDINECARBOXAMIDE DERIVATIVES NISSHIN PHARMA INC (JP) 2002-04-10 EP disclosed
US-6046201-A Pyridinecarboxamide derivatives NISSHIN FLOUR MILLING CO., LTD. (JP) 2000-04-04 US disclosed
EP-0882716-A1 PYRIDINECARBOXAMIDE DERIVATIVES Nisshin Flour Milling Co., Ltd. (JP) 1998-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210179939-A1 Organic Ligands For Templatable Mesoscale Nanocapsules EPCAM, L1CAM, ICOSLG TDP1 4047/4885CA1 1575/4885CA2 3440/4885
US-11708530-B2 Organic ligands for templatable mesoscale nanocapsules EPCAM, L1CAM, ICOSLG TDP1 4047/4885CA1 1575/4885CA2 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.