SCHEMBL5056436

SCHEMBL5056436

CCN(CC)CC/C=C1/c2ccccc2COc2ccc(C(=O)O)cc21

nearest known ligand 0.92

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TBXA2R P21731 6/20 0.60
▸ HRH1 P35367 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ TBXAS1 P24557 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750039 1.00 TBXA2R (0.60) TBXA2RHRH1LMNATBXAS1
SCHEMBL5056433 1.00 TBXA2R (0.60) TBXA2RHRH1LMNATBXAS1
SCHEMBL9750035 1.00 TBXA2R (0.60) TBXA2RHRH1LMNATBXAS1
SCHEMBL9749504 1.00 TBXA2R (0.60) TBXA2RHRH1LMNATBXAS1
SCHEMBL5056578 0.89 HRH1 (0.74) HRH1LMNA
SCHEMBL5056536 0.89 HRH1 (0.74) HRH1LMNA
SCHEMBL9749914 0.89 HRH1 (0.74) HRH1LMNA
SCHEMBL9749916 0.89 HRH1 (0.74) HRH1LMNA
SCHEMBL5056588 0.89 HRH1 (0.74) HRH1LMNA
SCHEMBL9750385 0.89 HRH1 (0.55) HRH1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080139531-A1 USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR ALCON MANUFACTURING LTD. (US) 2008-06-12 — — US claimed
US-20080139531-A1 USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR ALCON MANUFACTURING LTD. (US) 2008-06-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139531-A1 USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR CMA1, LTK, KIT TBXA2R 1003/4885HRH1 35/4885LMNA 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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