Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056498 | 1.00 | HRH1 (0.55) | HRH1LMNAPARP1 | |
| SCHEMBL5056502 | 1.00 | HRH1 (0.55) | HRH1LMNAPARP1 | |
| SCHEMBL9749546 | 0.90 | HRH1 (0.67) | HRH1LMNAPARP1 | |
| SCHEMBL30783267 | 0.90 | HRH1 (0.67) | HRH1LMNAPARP1 | |
| SCHEMBL5066512 | 0.90 | HRH1 (0.67) | HRH1LMNAPARP1 | |
| SCHEMBL5060455 | 0.90 | HRH1 (0.67) | HRH1LMNAPARP1 | |
| SCHEMBL9750035 | 0.89 | TBXA2R (0.60) | HRH1LMNA | |
| SCHEMBL5056436 | 0.89 | TBXA2R (0.60) | HRH1LMNA | |
| SCHEMBL5056433 | 0.89 | TBXA2R (0.60) | HRH1LMNA | |
| SCHEMBL9750039 | 0.89 | TBXA2R (0.60) | HRH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |