Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363698 | 0.85 | NPC1 (0.59) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL17477692 | 0.79 | BRD4 (0.51) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL7109188 | 0.79 | NPC1 (0.43) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL27141379 | 0.78 | NPC1 (0.52) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL4739140 | 0.77 | KMT2A (0.45) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL7037632 | 0.77 | EGLN1 (0.51) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11535108 | 0.77 | BRD4 (0.50) | NPC1RAB9AALDH1A1POLBBRD4 | |
| SCHEMBL6304052 | 0.76 | BRD4 (0.44) | NPC1RAB9AALDH1A1POLBBRD4 | |
| SCHEMBL25313164 | 0.75 | NPC1 (0.48) | NPC1KMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL1137531 | 0.75 | BRD4 (0.70) | KMT2ARAB9AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080054171-A1 | Target for Laser Desorption/Ionisation Mass Spectrometry | PHYSIKALISCHES BURO STEINMULLER GMBH | 2008-03-06 | — | — | US | disclosed |
| US-4132795-A | Benzenesulfonyl ureas and their use for the treatment of diabetes mellitus | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |