Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 16/20 | 0.64 |
| ▸ | CA1 | P00915 | 15/20 | 0.64 |
| ▸ | CA2 | P00918 | 15/20 | 0.64 |
| ▸ | CA12 | O43570 | 7/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24444501 | 0.90 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20999896 | 0.88 | CA1 (0.59) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14642801 | 0.88 | CA1 (0.67) | CA9CA1CA2CA12CA14 | |
| SCHEMBL23027406 | 0.86 | CA1 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13915130 | 0.86 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL5057128 | 0.86 | CA9 (0.59) | CA9CA1CA2CA12CA14 | |
| SCHEMBL18653006 | 0.86 | CA1 (0.65) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12678101 | 0.85 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL5057140 | 0.85 | ALB (0.50) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14754541 | 0.85 | CA1 (0.67) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7862807-B2 | Dendrimers as molecular translocators | UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080221020-A1 | Dendrimers as Molecular Translocators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-11 | — | — | US | disclosed |
| US-20060216265-A1 | Dendrimers as molecular translocators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-09-28 | — | — | US | disclosed |
| WO-2004009666-A2 | DENDRIMERS AS MOLECULAR TRANSLOCATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060216265-A1 | Dendrimers as molecular translocators | SLC29A1, SLC29A2, TSPO | CA9 3425/4885CA1 4290/4885CA2 2620/4885 |
| US-20080221020-A1 | Dendrimers as Molecular Translocators | SLC29A1, SLC29A2, TSPO | CA9 3425/4885CA1 4290/4885CA2 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.