SCHEMBL505741

SCHEMBL505741

C=CCN(CC=C)CCOC(=O)C(=C)C

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
KDM4E B2RXH2 10/20 0.43
KMT2A Q03164 6/20 0.43
MEN1 O00255 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 9/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 3/20 0.37
ATM Q13315 2/20 0.37
HPGD P15428 1/20 0.37
POLB P06746 2/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL719482 0.94 THRB (0.41) THRBTSHRKDM4EKMT2AMEN1
SCHEMBL2051778 0.90 TSHR (0.50) THRBTSHRKDM4EKMT2AMEN1
SCHEMBL746457 0.85 THRB (0.55) THRBTSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL618085 0.83 KDM4E (0.46) TSHRKDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL5321857 0.81 TSHR (0.42) THRBTSHRKDM4EKMT2AMEN1
Acrylic Acid SCHEMBL7775514 0.81 THRB (0.46) THRBTSHRKMT2AMEN1SMN1; SMN2
SCHEMBL12859989 0.81 TSHR (0.46) THRBTSHRKDM4ESMN1; SMN2ALDH1A1
SCHEMBL5455475 0.80 MEN1 (0.50) THRBTSHRKDM4EKMT2AMEN1
SCHEMBL9686279 0.80 TSHR (0.41) THRBTSHRKDM4EKMT2AMEN1
SCHEMBL9485408 0.79 THRB (0.50) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180822-A1 NON-NANOPARTICULATE APPLICATION FORMS OF MACROLIDES NUCLEUS MEDICAL GMBH (DE) 2024-06-06 US claimed
EP-4355300-A1 NON-NANOPARTICULATE APPLICATION FORMS OF MACROLIDES Nucleus Medical GmbH (DE) 2024-04-24 EP claimed
CN-117820526-A Modified ionic surfactant, preparation method thereof, water-based cleaning agent containing modified ionic surfactant and application of water-based cleaning agent 蒲城鲲鹏半导体材料有限公司 2024-04-05 CN claimed
CN-117597107-A Macrolides in non-nanoparticle applications 核心医疗有限公司 2024-02-23 CN claimed
EP-3730524-B1 METHOD FOR PRODUCING ANIONIC WATER-SOLUBLE POLYMER ON THE BASIS OF BIOACRYLAMIDE AND ACRYLIC ACID SNF GROUP (FR) 2024-02-07 EP claimed
US-11702513-B2 Aqueous dispersion of hydrosoluble or hydroswellable polymer S.P.C.M. SA (FR) 2023-07-18 US claimed
EP-3795664-B1 WATER-SOLUBLE OR WATER-SWELLABLE POLYMER AQUEOUS DISPERSION SPCM SA (FR) 2023-01-25 EP claimed
WO-2022263463-A1 NON-NANOPARTICULATE APPLICATION FORMS OF MACROLIDES NUCLEUS MEDICAL GMBH (DE) 2022-12-22 WO claimed
EP-4104816-A1 NON-NANOPARTICULATE APPLICATIONS FORMS OF MACROLIDES Nucleus Medical GmbH (DE) 2022-12-21 EP claimed
EP-3386288-B1 SEED TREATMENT USING HYDROSWELLABLE POLYMER SPCM SA (FR) 2021-11-10 EP claimed
EP-0215978-B1 LIQUID ELECTROPHORETIC DEVELOPER COMPOSITION AGFA-GEVAERT N.V. (BE) 1990-03-21 EP claimed
EP-0356592-A1 Process for producing emulsion polymer composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-03-07 EP claimed
EP-0245930-A2 Reducing fluid loss in downhole cementing HALLIBURTON COMPANY (US) 1987-11-19 EP claimed
EP-0215978-A1 Liquid electrophoretic developer composition AGFA-GEVAERT N.V. (BE) 1987-04-01 EP claimed
US-4642601-A Humidity-sensitive element HITACHI, LTD. (JP) 1987-02-10 US claimed
US-4520008-A ADDITION POLYMER AND PROPYLENE OXIDE-ETHYLENE OXIDE ADDUCT OF A FATTY ALCOHOL; TEXTURE KAO SOAP CO., LTD. (JP) 1985-05-28 US claimed
US-4454219-A Photosensitive resin composition comprised of a polymer obtained from an aliphatic amino group-containing monomer as a comonomer HITACHI CHEMICAL COMPANY, LTD. (JP) 1984-06-12 US claimed
US-4443497-A DISSOLVING, COATING, SOLVENTS, POLYMER, ETHYL CELLULOSE, ANTICOAGULANTS, DRUGS TANABE SEIYAKU CO., LTD. (JP) 1984-04-17 US claimed
US-4273873-A BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME UNITIKA LTD. (JP) 1981-06-16 US claimed
US-4158726-A HIGH MOLECULAR WEIGHT, WATER-SOLUBLE CATIONIC ACRYLIC OR METHACRYLIC ESTER POLYMERS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1979-06-19 US claimed