Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.73 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CDC42 | P60953 | 1/20 | 0.73 |
| ▸ | RAC1 | P63000 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508603 | 1.00 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505799 | 1.00 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL8754690 | 1.00 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29403959 | 1.00 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505811 | 1.00 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL11015007 | 0.97 | TDP1 (0.73) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL14364989 | 0.91 | TDP1 (0.65) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL12744118 | 0.91 | TDP1 (0.69) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL9551659 | 0.90 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL12744138 | 0.89 | PTGS2 (0.63) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319952-B2 | Method for enzymatic resolution of chiral substances | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2025-06-03 | — | — | US | claimed |
| CN-115646522-B | Preparation method of potassium ion doped carbon nitride silicon dioxide heterojunction, product and application thereof | 浙江大学杭州国际科创中心 | 2024-03-22 | — | — | CN | claimed |
| CN-113862117-B | Device and method for separating chiral substances by multi-liquid-phase system continuous enzyme method | 华南理工大学 | 2024-03-12 | — | — | CN | claimed |
| CN-114457055-B | Carboxylesterase, coding gene, genetically engineered bacterium and application thereof | 浙江工业大学 | 2023-08-25 | — | — | CN | claimed |
| CN-115646522-A | Preparation method of potassium ion doped silicon nitride-carbon oxide heterojunction, product and application thereof | 浙江大学杭州国际科创中心 | 2023-01-31 | — | — | CN | claimed |
| CN-115613062-A | Method for electrochemically preparing bromide | 浙江大学杭州国际科创中心 | 2023-01-17 | — | — | CN | claimed |
| CN-109464670-B | Key amino acid site for regulating and controlling nucleoprotein nuclear production of influenza A virus and influenza B virus and application of key amino acid site as anti-influenza virus drug target | 中国科学院微生物研究所 | 2022-08-02 | — | — | CN | claimed |
| CN-110078618-B | Method for preparing s- (+) naproxen methyl ester by asymmetric catalysis method | 常州大学 | 2022-03-01 | — | — | CN | claimed |
| US-20220017935-A1 | A Method for Enzymatic Resolution of Chiral Substances | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2022-01-20 | — | — | US | claimed |
| CN-113862117-A | Device and method for splitting chiral substance by multi-liquid-phase system continuous enzymatic method | 华南理工大学 | 2021-12-31 | — | — | CN | claimed |
| CN-101880695-A | Method for preparing (S)-naproxen by enzyme resolution of racemic naproxen ester | UNIV EAST CHINA SCIENCE & TECH | 2010-11-10 | — | — | CN | claimed |
| CN-101486643-A | Trans naproxen ester, optical isomer thereof, as well as preparation and use thereof | UNIV HUNAN (CN) | 2009-07-22 | — | — | CN | claimed |
| CN-1584037-A | Method for biological catalytic preparing naprosyn | LANZHOU CHEM PHYS INST (CN) | 2005-02-23 | — | — | CN | claimed |
| CN-1131196-C | Process for rapidly racemizing naproxen methylester by microwave method | LANZHOU INST CHEMICOPHYSICS (CN) | 2003-12-17 | — | — | CN | claimed |
| CN-1086422-C | Method for preparation of S-(+)-naprosyn by enzyme catalysis of asymmetrical hydrolysis reaction | LANZHOU CHEMICOPHYSICS INST CH (CN) | 2002-06-19 | — | — | CN | claimed |
| CN-1327974-A | Process for rapidly racemizing naproxen methylester by microwave method | LANZHOU INST CHEMICOPHYSICS (CN) | 2001-12-26 | — | — | CN | claimed |
| CN-1305008-A | Process for preparing S-(t)-naphthroxen | LANZHOU INST CHEMICOPHYSICS (CN) | 2001-07-25 | — | — | CN | claimed |
| CN-1055933-C | Polyclonal antibody, preparing process and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2000-08-30 | — | — | CN | claimed |
| CN-1260400-A | Method for preparation of S-(+)-naprosyn by enzyme catalysis of asymmetrical hydrolysis reaction | LANZHOU CHEMICOPHYSICS INST CH (CN) | 2000-07-19 | — | — | CN | claimed |
| CN-1212254-A | Method for preparing naproxen of methyl ester and S-(+) naproxen of methyl ester by using carbonylation | LANZHOU CHEM PHYS INST (CN) | 1999-03-31 | — | — | CN | claimed |