Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.30 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555790 | 0.86 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL14252261 | 0.83 | TDP1 (0.41) | TDP1TSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL29220272 | 0.81 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL7922554 | 0.81 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL8991844 | 0.79 | CYP3A4 (0.37) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL536216 | 0.78 | — | — | |
| SCHEMBL1260841 | 0.78 | CYP3A4 (0.36) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL7083075 | 0.77 | TSHR (0.39) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL5428036 | 0.77 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL177943 | 0.77 | CYP3A4 (0.48) | TDP1TSHRCYP3A4MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125354-A1 | SELECTIVE INHIBITION OF MATRIX METALLOPROTEINASES | FLORIDA ATLANTIC UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-7338748-B2 | Polymerizable composition and planographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |
| WO-2007062376-A2 | SELECTIVE INHIBITION OF MATRIX METALLOPROTEINASES | FLORIDA ATLANTIC UNIVERSITY (US) | 2007-05-31 | — | — | WO | disclosed |