Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774713 | 0.82 | ALDH1A1 (0.64) | AKR1C3MAPTGAAKDM4EMCL1 | |
| SCHEMBL11562388 | 0.82 | AKR1C3 (0.56) | AKR1C3MAPTGAAKDM4EBCL2 | |
| 5-Amino-2-Benzoylbenzoic Acid SCHEMBL31333092 | 0.80 | AKR1C3 (0.62) | AKR1C3MAPTGAAKDM4EPBRM1 | |
| SCHEMBL11147848 | 0.80 | KDM4E (0.68) | AKR1C3MAPTGAAKDM4EPBRM1 | |
| 5-Amino-2-Benzoylbenzoic Acid SCHEMBL8999371 | 0.80 | AKR1C3 (0.62) | AKR1C3MAPTGAAKDM4EPBRM1 | |
| SCHEMBL10762907 | 0.77 | MAPT (0.50) | AKR1C3MAPTGAAKDM4EPBRM1 | |
| SCHEMBL690151 | 0.77 | AKR1C3 (0.69) | AKR1C3MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL31668557 | 0.77 | AKR1C3 (0.69) | AKR1C3MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL15313729 | 0.77 | BCL2 (0.68) | AKR1C3MAPTGAAKDM4EBCL2 | |
| SCHEMBL5194327 | 0.76 | ALDH1A1 (0.63) | AKR1C3MAPTGAAKDM4EPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883619-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | Choongwae Pharma Corporation (KR) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126846-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORPORATION (KR) | 2006-11-30 | — | — | WO | disclosed |