Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 2/20 | 0.65 |
| ▸ | CES1 | P23141 | 2/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27308628 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL28215855 | 0.95 | TSHR (0.62) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL29006318 | 0.95 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL27743198 | 0.92 | TSHR (0.65) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3477053 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL21324536 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL1768920 | 0.92 | TSHR (0.71) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL8249 | 0.92 | TSHR (0.71) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL9717815 | 0.92 | TSHR (0.71) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL7648718 | 0.92 | TSHR (0.71) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226913-B | Frame coordination material with tetranuclear cobalt as node and preparation method thereof | 江汉大学 | 2021-03-09 | — | — | CN | disclosed |
| EP-1931760-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | The University of Alabama (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007044693-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | THE UNIVERSITY OF ALABAMA (US) | 2007-04-19 | — | — | WO | disclosed |
| EP-1423371-A1 | TRIAZINE DERIVATIVES AND THEIR USE AS SUNSCREENS | Ciba SC Holding AG (CH) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003016289-A1 | TRIAZINE DERIVATIVES AND THEIR USE AS SUNSCREENS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-02-27 | — | — | WO | disclosed |
| EP-0563302-A1 | METHOD AND APPARATUS FOR GRANULATION | WASHINGTON UNIVERSITY TECHNOLOGY ASSOCIATES, INC. (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011120-A1 | METHOD AND APPARATUS FOR GRANULATION | WASHINGTON UNIVERSITY TECHNOLOGY ASSOCIATES, INC (US) | 1992-07-09 | — | — | WO | disclosed |
| US-5100592-A | Method and apparatus for granulation and granulated product | WASHINGTON UNIVERSITY TECHNOLOGY ASSOCIATED, INC. (US) | 1992-03-31 | — | — | US | disclosed |