Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | DAO | P14920 | 1/20 | 0.74 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.74 |
| ▸ | CES2 | O00748 | 3/20 | 0.61 |
| ▸ | CES1 | P23141 | 3/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21324536 | 1.00 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL27743198 | 0.95 | TSHR (0.65) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27308628 | 0.95 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL28215855 | 0.92 | TSHR (0.62) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL5058591 | 0.92 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzidine SCHEMBL31326213 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Aminobenzoic Acid SCHEMBL29006318 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8921181 | 0.86 | CA6 (0.62) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3044510 | 0.86 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6869498 | 0.86 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426666-B | Polyimide film and method for producing the same | 臻鼎科技股份有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-116334807-B | Preparation method of high-strength polyester fiber lifting belt | 德清申力索具有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-112142610-B | Synthesis method of N-phenyl aminobenzoic acid | 上海沃凯生物技术有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116334807-A | Preparation method of high-strength polyester fiber lifting belt | 德清申力索具有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-112142610-A | Synthesis method of N-phenylaminobenzoic acid | 上海沃凯生物技术有限公司 | 2020-12-29 | — | — | CN | claimed |
| WO-2010130309-A1 | AQUEOUS PREPARATIONS HAVING LIQUID CRYSTALLINE PROPERTIES | BASF COATINGS AG (DE) | 2010-11-18 | — | — | WO | claimed |
| CN-112142610-B | Synthesis method of N-phenyl aminobenzoic acid | 上海沃凯生物技术有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114929874-A | Plant colonization assay using native microbial barcodes | 皮沃特生物股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114174504-A | Subtilisin variants and methods of use | 丹尼斯科美国公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113166682-A | Composition for cleaning medical instruments | 丹尼斯科美国公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112697956-A | Method for detecting vanadium content in vanadium-containing alloy | 攀钢集团江油长城特殊钢有限公司 | 2021-04-23 | — | — | CN | disclosed |
| CN-112142610-A | Synthesis method of N-phenylaminobenzoic acid | 上海沃凯生物技术有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-112142610-A | Synthesis method of N-phenylaminobenzoic acid | 上海沃凯生物技术有限公司 | 2020-12-29 | — | — | CN | disclosed |
| US-5378694-A | Herpes viricide, hypotensive agent | SCHERING CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0550464-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1993-07-14 | — | — | EP | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004328-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| US-5025082-A | Soldering resistance; molding materials for electronics | MITSUBISHI KASEI CORPORATION (JP) | 1991-06-18 | — | — | US | disclosed |
| US-4397649-A | Water-soluble phthalocyanine sulfonyl cyanamide compounds, process for their manufacture and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-09 | — | — | US | disclosed |