SCHEMBL505901

SCHEMBL505901

CCCCCC1=C(CCCCC)C(=O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
THRB P10828 1/20 0.46
ALOX5 P09917 9/20 0.40
MPEG1 Q2M385 7/20 0.40
CDC25A P30304 6/20 0.40
CDC25B P30305 6/20 0.40
CDC25C P30307 5/20 0.40
GPR84 Q9NQS5 5/20 0.40
XIAP P98170 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
PTGES O14684 1/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28925304 0.98 ALDH1A1 (0.48) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL28642404 0.98 ALDH1A1 (0.48) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL27624280 0.98 ALDH1A1 (0.48) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL27644549 0.98 ALDH1A1 (0.48) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL27624286 0.98 ALDH1A1 (0.48) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL4005667 0.93 ALDH1A1 (0.42) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL27643712 0.92 ALDH1A1 (0.38) ALDH1A1MAPTTDP1THRBALOX5
Ethylene Glycol SCHEMBL27585985 0.89 ALDH1A1 (0.43) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL1535496 0.87 ALDH1A1 (0.49) ALDH1A1MAPTTDP1THRBALOX5
SCHEMBL5722122 0.85 ALDH1A1 (0.51) ALDH1A1MAPTTDP1THRBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907249-A Ring chain heterogeneous stilbene fluorescent molecule, preparation method and application 中国科学院福建物质结构研究所 2022-08-16 CN claimed
CN-107056673-B 3, 4-diaryl maleimide derivative and preparation method and application thereof NANJING TECH UNIVERSITY (CN) 2019-10-29 CN claimed
CN-107056673-A 3, 4-diaryl maleimide derivative and preparation method and application thereof 南京工业大学 2017-08-18 CN claimed
CN-104447489-B 3, 4-diaryl maleimide derivative and preparation method and application thereof 南京工业大学 2017-01-11 CN claimed
CN-104447489-A 3, 4-diaryl maleimide derivative and preparation method and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-03-25 CN claimed
CN-102838983-A Maleimide fluorescence sensor including trifluoroacetamide and preparation method UNIV FUJIAN 2012-12-26 CN claimed
WO-2009148454-A1 METHOD OF MODIFYING A LENS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-10 WO claimed
US-20080137032-A1 Optical lens and method of manufacturing GENERAL ELECTRIC COMPANY (US) 2008-06-12 US claimed
US-20080055686-A1 Holographic data recording method and system SABIC INNOVATIVE PLASTICS IP B.V. 2008-03-06 US claimed
WO-2007075951-A2 METHODS FOR STORING HOLOGRAPHIC DATA AND ARTICLES HAVING ENHANCED DATA STORAGE LIFETIME DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-07-05 WO claimed
US-20070147214-A1 Methods for storing holographic data and articles having enhanced data storage lifetime derived therefrom GENERAL ELECTRIC COMPANY (US) 2007-06-28 US claimed
EP-1797557-A1 HOLOGRAPHIC STORAGE MEDIUM General Electric Company (US) 2007-06-20 EP claimed
WO-2006039130-A1 HOLOGRAPHIC STORAGE MEDIUM GENERAL ELECTRIC COMPANY (US) 2006-04-13 WO claimed
US-20060073392-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-06 US claimed
CN-114907249-A Ring chain heterogeneous stilbene fluorescent molecule, preparation method and application 中国科学院福建物质结构研究所 2022-08-16 CN disclosed
CN-107056673-B 3, 4-diaryl maleimide derivative and preparation method and application thereof NANJING TECH UNIVERSITY (CN) 2019-10-29 CN disclosed
CN-104447489-B 3, 4-diaryl maleimide derivative and preparation method and application thereof 南京工业大学 2017-01-11 CN disclosed
US-6258954-B1 ELECTROLUMINESCENCE; DETECTION VOIDS CIBA SPECIALTY CHEMICALS CORP. 2001-07-10 US disclosed
WO-2001019939-A1 FLUORESCENT MALEIMIDES AND USES THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO disclosed
US-5529864-A CONTAINING PHOTOCHROMIC DYE DISPERSED IN LIQUID CRYSTALLINE POLYMER CANON KABUSHIKI KAISHA (JP) 1996-06-25 US disclosed