Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663294 | 1.00 | KMT2A (0.33) | KMT2AMEN1TP53CA1CA9 | |
| SCHEMBL664239 | 0.89 | KMT2A (0.37) | KMT2AMEN1TP53CA1CA9 | |
| SCHEMBL13930055 | 0.77 | KMT2A (0.36) | KMT2AMEN1TP53CA1CA9 | |
| SCHEMBL664811 | 0.77 | KMT2A (0.36) | KMT2AMEN1TP53CA1CA9 | |
| SCHEMBL23671884 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL14360218 | 0.71 | KMT2A (0.40) | KMT2AMEN1TP53CA1CA9 | |
| SCHEMBL10756094 | 0.70 | CYP1A2 (0.34) | — | |
| SCHEMBL22341905 | 0.66 | CYP1A2 (0.33) | — | |
| SCHEMBL10309467 | 0.66 | ALDH1A1 (0.37) | — | |
| SCHEMBL12547904 | 0.66 | HIF1A (0.38) | KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004773-A2 | COMPOSITIONS COMPRISING A FLUOROOLEFIN | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007126414-A2 | COMPOSITIONS COMPRISING A FLUOROOLEFIN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-08 | — | — | WO | disclosed |