SCHEMBL5060643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5054928	0.93	KDR (0.60)	KDRROCK2MAP4K4LCKRET
	SCHEMBL5056678	0.89	KDR (0.55)	KDRMAP3K7ROCK2RETAURKB
	SCHEMBL5054944	0.88	KDR (0.62)	KDRROCK2MAP4K4LCKRET
	SCHEMBL5056268	0.86	PTK2 (0.60)	KDRROCK2MAP4K4LCKRET
	SCHEMBL5056379	0.86	KDR (0.55)	KDRMAP3K7ROCK2MAP4K4LCK
	SCHEMBL5052256	0.85	KDR (0.58)	KDRROCK2MAP4K4LCKRET
	SCHEMBL2084882	0.85	MAPK14 (0.67)	KDRROCK2MAP4K4LCKRET
	SCHEMBL2085188	0.85	KDR (0.52)	KDRROCK2MAP4K4LCKRET
	SCHEMBL2082144	0.84	KDR (0.53)	KDRROCK2MAP4K4LCKRET
	SCHEMBL5060551	0.84	KDR (0.53)	KDRROCK2MAP4K4LCKRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.