SCHEMBL5060909

SCHEMBL5060909

CCOP(=O)(OCC)c1cc(I)sc1I

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.32
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492190 0.74 POLB (0.33) POLBMEN1KMT2A
SCHEMBL2494196 0.71 POLB (0.41) POLBMEN1KMT2ATSHRTP53
SCHEMBL2493165 0.71 TSHR (0.39) POLBMEN1KMT2ATSHRTP53
SCHEMBL2494264 0.70 POLB (0.41) POLBMEN1KMT2ATSHR
SCHEMBL12191825 0.69 POLB (0.42) POLBMEN1KMT2ATSHRTP53
SCHEMBL12191822 0.69 POLB (0.42) POLBMEN1KMT2ATSHRTP53
SCHEMBL12191831 0.69 POLB (0.42) POLBMEN1KMT2ATSHRTP53
SCHEMBL2493216 0.69 POLB (0.44) POLBMEN1KMT2ATSHRTP53
SCHEMBL14309676 0.68 POLB (0.41) POLBMEN1KMT2ATSHRTP53
SCHEMBL2498021 0.68 POLB (0.35) POLBMEN1KMT2ATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1882694-B1 OLIGOMERS AND POLYMERS OF THIOPHENE COMPOUNDS HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME NISSAN CHEMICAL IND LTD (JP) 2013-04-03 EP disclosed
EP-1882694-A1 THIOPHENE COMPOUND HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2008-01-30 EP disclosed