⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313054 | 0.93 | ALDH1A1 (0.31) | — | |
| SCHEMBL19965899 | 0.91 | — | — | |
| SCHEMBL3668462 | 0.84 | — | — | |
| SCHEMBL6737496 | 0.81 | — | — | |
| SCHEMBL11733720 | 0.79 | — | — | |
| SCHEMBL11734619 | 0.78 | — | — | |
| SCHEMBL20153306 | 0.78 | — | — | |
| SCHEMBL11733641 | 0.76 | — | — | |
| SCHEMBL11742817 | 0.76 | — | — | |
| SCHEMBL11737250 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574821-B | Intermediate for synthesis of teprenone and application thereof | 黄冈鲁班药业股份有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-108997463-B | Preparation method of estra-4, 9-diene-3, 17-dione | 四川理工学院 | 2021-05-14 | — | — | CN | claimed |
| CN-109574821-A | A kind of new intermediate of Teprenone synthesis and its application | 黄冈鲁班药业股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108997463-A | A kind of female steroid -4,9- diene -3,17- diketone preparation method | 四川理工学院 | 2018-12-14 | — | — | CN | claimed |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| US-20250074930-A1 | ORGANOTIN COMPOSITIONS HAVING LIGANDS WITH ACETAL FUNCTIONAL GROUPS, PATTERNING COMPOSITIONS WITH ORGANOTIN BLENDS AND POSITIVE TONE PATTERNING | INPRIA CORPORATION | 2025-03-06 | — | — | US | disclosed |
| WO-2025049424-A1 | ORGANOTIN COMPOSITIONS HAVING LIGANDS WITH ACETAL FUNCTIONAL GROUPS, PATTERNING COMPOSITIONS WITH ORGANOTIN BLENDS AND POSITIVE TONE PATTERNING | INPRIA CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-111995574-B | Deuterated hydroxychloroquine derivative and pharmaceutical composition containing same | 西安明喆药品生产有限公司 | 2024-05-17 | — | — | CN | disclosed |
| US-11884661-B2 | 3-substituted propionic acids as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| US-3997670-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3996374-A | Isoindole derivatives as appetite suppressants | HOFFMANN-LA ROCHE INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3994926-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3972896-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-08-03 | — | — | US | disclosed |
| US-3960895-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3960896-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3950358-A | ARYL KETALS OF 3,7-DIHYDROXY-11-OXO-DODEC-1-ENE | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |
| US-3948951-A | Aryl ketals of 1-chloro-4-oxo-pentane | HOFFMANN-LA ROCHE INC. (US) | 1976-04-06 | — | — | US | disclosed |