Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591474 | 0.83 | MGLL (0.49) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL9171144 | 0.78 | MGLL (0.50) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL1728478 | 0.76 | MGLL (0.67) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL3623489 | 0.71 | — | — | |
| SCHEMBL1867164 | 0.71 | — | — | |
| SCHEMBL19207 | 0.71 | — | — | |
| SCHEMBL29351152 | 0.70 | GAA (0.41) | MGLLFAAHHSP90AA1PKMATM | |
| SCHEMBL4289308 | 0.70 | GAA (0.41) | MGLLFAAHHSP90AA1PKMATM | |
| Phosphine SCHEMBL19611318 | 0.70 | — | — | |
| Water SCHEMBL3416842 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318209-A1 | Cjd Prion Testing | PROTHERICS MOLECULAR DESIGN LTD. (GB) | 2008-12-25 | — | — | US | disclosed |
| EP-1714159-A2 | CJD PRION TESTING | Protherics Molecular Design Limited (GB) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073731-A2 | CJD PRION TESTING | PROTHERICS MOLECULAR DESIGN LIMITED (GB) | 2005-08-11 | — | — | WO | disclosed |