SCHEMBL5062195

SCHEMBL5062195

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nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PYGB P11216 9/20 0.48
PYGL P06737 3/20 0.40
PYGM P11217 2/20 0.40
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28575710 1.00 PYGB (0.48) PYGBPYGLPYGMSELLSELP
SCHEMBL2844313 0.85 PYGB (0.57) PYGBPYGLPYGM
SCHEMBL17781741 0.84 PYGB (0.43) PYGBPYGLPYGM
SCHEMBL28356506 0.83 PYGB (0.44) PYGBPYGLPYGM
SCHEMBL7580441 0.83 PYGB (0.41) PYGBPYGLPYGM
SCHEMBL5988585 0.78 PYGB (0.36) PYGBPYGLPYGM
SCHEMBL14977692 0.77 PYGB (0.37) PYGBPYGLPYGM
SCHEMBL1665805 0.77 MAPK1 (0.44) PYGB
SCHEMBL2122988 0.77 MAPK1 (0.44) PYGB
SCHEMBL9095367 0.77 PYGB (0.40) PYGBPYGLPYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080076906-A1 Antagonists of neuropilin receptor function and use thereof CHILDREN'S MEDICAL CENTER CORPORATION (US) 2008-03-27 US disclosed