Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506239 | 1.00 | NAAA (0.65) | NAAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| Cyclohexanecarboxylic Acid Pentadecylamide SCHEMBL28082344 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL27761005 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL28082867 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL8847632 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL28832373 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL28082885 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL17694453 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL6267383 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 | |
| SCHEMBL28082415 | 0.80 | NAAA (1.00) | NAAAEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853452-B2 | Compounds, their syntheses, compositions, and methods to treat cancer | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120027844-A1 | COMPOUNDS, THEIR SYNTHESES, COMPOSITIONS, AND METHODS TO TREAT CANCER | XAVIER UNIVERSITY OF LOUISIANA (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2010093615-A2 | COMPOUNDS, THEIR SYNTHESES, COMPOSITIONS, AND METHODS TO TREAT CANCER | TULANE UNIVERSITY (US) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027844-A1 | COMPOUNDS, THEIR SYNTHESES, COMPOSITIONS, AND METHODS TO TREAT CANCER | SGMS1, PHOSPHO1, MCL1 | NAAA 987/4885CHRNB2 4838/4885CHRNB4 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.