⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866329 | 0.83 | — | — | |
| SCHEMBL4146828 | 0.80 | — | — | |
| SCHEMBL18687786 | 0.75 | — | — | |
| SCHEMBL1157679 | 0.75 | — | — | |
| SCHEMBL8991000 | 0.73 | — | — | |
| SCHEMBL1184727 | 0.73 | LMNA (0.45) | — | |
| SCHEMBL6818449 | 0.73 | — | — | |
| SCHEMBL8541517 | 0.73 | — | — | |
| SCHEMBL8866099 | 0.73 | — | — | |
| SCHEMBL588236 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388014-A | Synthesis method of chiral alpha-aryl propionic acid derivative | DSM IP ASSETS BV | 2012-03-21 | — | — | CN | claimed |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | claimed |
| EP-2393771-A1 | Method for the synthesis of chiral alpha-aryl propionic acid derivatives | DSM IP Assets B.V. (NL) | 2011-12-14 | — | — | EP | claimed |
| WO-2010089343-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2010-08-12 | — | — | WO | claimed |
| US-20090131437-A1 | DISUBSTITUTED UREAS AS KINASE INHIBITORS | CORIUM INTERNATIONAL, INC. (US) | 2009-05-21 | — | — | US | claimed |
| EP-1838700-A2 | DISUBSTITUTED UREAS AS KINASE INHIBITORS | Novartis AG (CH) | 2007-10-03 | — | — | EP | claimed |
| CN-1950335-A | Novel biaromatic compounds which activate PPAR.gamma.-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-04-18 | — | — | CN | claimed |
| WO-2006072589-A2 | DISUBSTITUTED UREAS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2006-07-13 | — | — | WO | claimed |
| CN-1184200-C | Bi-aromatic compounds bond by a heteroethynytene radical and pharmaceutical and comsmetic compositions containing same | GALDERMA RES & DEV I (FR) | 2005-01-12 | — | — | CN | claimed |
| CN-1236359-A | Bi-aromatic compounds bond by a heteroethynytene radical and pharmaceutical and comsmetic compositions containing same | GALDERMA RES & DEV (FR) | 1999-11-24 | — | — | CN | claimed |
| EP-0519731-B1 | 4a-Substituted avermectin derivatives | MERCK & CO INC (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0537998-B1 | Controlled release drug delivery device comprising a polymer matrix and a plasticizer | MERCK & CO INC (US) | 1997-01-15 | — | — | EP | claimed |
| US-5411737-A | Flea and tick collars | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | claimed |
| US-5262400-A | Antiparasitic and anthelmintic | MERCK & CO., INC. (US) | 1993-11-16 | — | — | US | claimed |
| EP-0519731-A1 | 4a-Substituted avermectin derivatives | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | claimed |
| CN-118702552-A | Preparation method of methoxyethoxy chloromethane | 浙江国邦药业有限公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20230322742-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2023-10-12 | — | — | US | disclosed |
| EP-0519731-A1 | 4a-Substituted avermectin derivatives | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4217274-A | Methoxyethoxymethyl esters of penicillins | BRISTOL-MYERS COMPANY (US) | 1980-08-12 | — | — | US | disclosed |