Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064551 | 1.00 | PDE4D (0.65) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL5058868 | 0.94 | PDE4D (0.72) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL5064542 | 0.94 | PDE4D (0.57) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL5063387 | 0.89 | PDE4D (0.49) | PDE4DSMN1; SMN2PDE4BPDE4APDE4C | |
| SCHEMBL5066759 | 0.89 | PDE4D (0.62) | PDE4DKMT2ALMNANPSR1HPGD | |
| SCHEMBL5063197 | 0.89 | PDE4D (0.53) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL5058925 | 0.89 | PDE4D (0.53) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL5058936 | 0.84 | PDE4D (0.58) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL7704337 | 0.83 | PDE4D (0.77) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL7704339 | 0.83 | PDE4D (0.77) | PDE4DKMT2ALMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161339-A1 | Novel Thio-Containing Hydroxy-6-Phenylphenanthridines and their Use as Pde4 Inhibitors | ALTANA PHARMA AG (DE) | 2008-07-03 | — | — | US | claimed |
| US-20080161339-A1 | Novel Thio-Containing Hydroxy-6-Phenylphenanthridines and their Use as Pde4 Inhibitors | ALTANA PHARMA AG (DE) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161339-A1 | Novel Thio-Containing Hydroxy-6-Phenylphenanthridines and their Use as Pde4 Inhibitors | PDE4A, PDE4B, PDE4C | PDE4D 4/4885KMT2A 1874/4885LMNA 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.