Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064588 | 0.88 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL5068077 | 0.88 | AVPR2 (0.46) | AVPR2HSD17B3AVPR1A | |
| SCHEMBL5066806 | 0.84 | MAPT (0.45) | AVPR2 | |
| SCHEMBL5058877 | 0.84 | AVPR2 (0.62) | AVPR2AVPR1AOXTR | |
| SCHEMBL5068208 | 0.83 | NPC1 (0.42) | AVPR2AVPR1A | |
| SCHEMBL5064583 | 0.81 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL5064582 | 0.81 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL2960705 | 0.81 | HSD17B3 (0.43) | AVPR2HSD17B3AVPR1AOXTR | |
| SCHEMBL5068104 | 0.80 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL14339308 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1867639-A1 | UREA DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | AVPR2 1/4885HSD17B3 791/4885AVPR1A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.