Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL5893261 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL7781114 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL29249913 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL2821640 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL188156 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL6937868 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL1434088 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL29098547 | 0.96 | TSHR (0.44) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL504364 | 0.93 | TSHR (0.41) | TSHRLMNACA4FAHD1BLM | |
| Cadaverine Tartrate SCHEMBL440871 | 0.93 | CA4 (0.47) | TSHRLMNACA4FAHD1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183363-B1 | FUNGAL XYLANASE | DANISCO US INC (US) | 2016-06-08 | — | — | EP | disclosed |
| CN-101611001-B | Utilize the method for hydrosulphite Intermediate Preparation 6,6-dimethyl-3-azabicyclo-[3.1.0]-hexane compound | MERCK SHARP & DOHME CORP. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104781213-A | Pressure process | WZR ceramic solutions GmbH | 2015-07-15 | — | — | CN | disclosed |
| CN-103214483-B | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP | 2014-12-17 | — | — | CN | disclosed |
| CN-104136432-A | Industrial process for producing 1, 2-dihydroquinoline derivative or salt thereof and intermediate for producing the same | SANTEN PHARMACEUTICAL CO LTD | 2014-11-05 | — | — | CN | disclosed |
| CN-103254190-A | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP | 2013-08-21 | — | — | CN | disclosed |
| CN-103214484-A | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP A DELAWARE CORP | 2013-07-24 | — | — | CN | disclosed |
| CN-103214483-A | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP | 2013-07-24 | — | — | CN | disclosed |
| CN-102803481-A | Methods for reducing blue saccharide | DANISCO US INC | 2012-11-28 | — | — | CN | disclosed |
| CN-1474803-B | Amide derivatives and their use for the preparation of medicaments | MITSUBISHI TANABE PHARMA CORP | 2012-11-21 | — | — | CN | disclosed |
| CN-1474803-A | Novel amide derivative and medical use thereof | ������ҩ��ʽ���� | 2004-02-11 | — | — | CN | disclosed |
| CN-1428404-A | Combustion agent composition for generating colour brilliance lamp, and its mking method | JIN-MAN IM (KR) | 2003-07-09 | — | — | CN | disclosed |
| CN-1100056-C | Compound for inhibition of gastric acid secretion | ASTRA AB (SE) | 2003-01-29 | — | — | CN | disclosed |
| CN-1384222-A | Electroplating liquor without electrolytic copper and high-frequency electronic element | MURATA MANUFACTURING CO (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1272842-A | 2-acylaminopropanamines as tachykinin receptor antagonists | LILLY CO ELI (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1259138-A | 17 'beta'-allyloxy (thio) alkyl-androstane derivatives for the modulation of meiosis | AKZO NOBEL NV (NL) | 2000-07-05 | — | — | CN | disclosed |
| CN-1248257-A | Compound for inhibition of gastric acid secretion | ASTRA AB (SE) | 2000-03-22 | — | — | CN | disclosed |
| EP-0327057-B1 | Process for metalizing fibrous materials | TEXMET SPA (IT) | 1994-04-13 | — | — | EP | disclosed |
| US-5035924-A | Process for metallizing fibrous materials | HIMONT ITALIA S.R.L. (IT) | 1991-07-30 | — | — | US | disclosed |
| EP-0327057-A1 | Process for metalizing fibrous materials | TEXMET S.p.A. (IT) | 1989-08-09 | — | — | EP | disclosed |