Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.65 |
| ▸ | MMP2 | P08253 | 8/20 | 0.65 |
| ▸ | MMP8 | P22894 | 7/20 | 0.65 |
| ▸ | MMP10 | P09238 | 7/20 | 0.65 |
| ▸ | MMP3 | P08254 | 2/20 | 0.57 |
| ▸ | MMP12 | P39900 | 2/20 | 0.57 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475001 | 0.89 | MMP13 (0.74) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL688391 | 0.87 | MMP13 (0.64) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL1478155 | 0.86 | MMP13 (0.57) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL10289677 | 0.84 | MMP13 (0.75) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL689176 | 0.83 | MMP13 (0.74) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL688571 | 0.81 | MMP13 (0.71) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL4934733 | 0.80 | MMP13 (0.72) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL1475050 | 0.80 | MMP13 (0.68) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL689629 | 0.80 | MMP13 (0.74) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL689368 | 0.79 | MMP13 (0.69) | MMP13MMP2MMP8MMP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-08-06 | — | — | EP | disclosed |