Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyrazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL20495491 | 1.00 | — | — | |
| Oxalic Acid SCHEMBL27705066 | 0.92 | HCAR2 (0.30) | HCAR2 | |
| Oxalic Acid SCHEMBL27899728 | 0.92 | HCAR2 (0.30) | HCAR2 | |
| Pyrazole SCHEMBL27812310 | 0.90 | — | — | |
| Pyrazole SCHEMBL4114829 | 0.90 | — | — | |
| Pyrazole SCHEMBL440249 | 0.90 | — | — | |
| Pyrazole SCHEMBL1768971 | 0.90 | — | — | |
| Benzene SCHEMBL27522565 | 0.88 | — | — | |
| Benzene SCHEMBL27971048 | 0.88 | — | — | |
| Pyrazole SCHEMBL28050126 | 0.87 | FFAR3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2798013-A1 | ANTI-REFLECTIVE COATING | Leibniz-Institut für Neue Materialien gemeinnützige GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013098090-A1 | ANTI-REFLECTIVE COATING | LEIBNIZ-INSTITUT FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2001825-A1 | METHOD FOR COMMERCIALLY OBTAINING PROPENE | BASF SE (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007113118-A1 | METHOD FOR COMMERCIALLY OBTAINING PROPENE | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |