⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650 | 0.82 | GBA1 (0.42) | — | |
| SCHEMBL3515320 | 0.79 | CYP11B1 (0.41) | — | |
| SCHEMBL507025 | 0.78 | — | — | |
| SCHEMBL4768617 | 0.77 | ADRA2A (0.39) | — | |
| SCHEMBL668445 | 0.76 | — | — | |
| SCHEMBL22703601 | 0.76 | — | — | |
| SCHEMBL15334882 | 0.76 | — | — | |
| SCHEMBL14847463 | 0.76 | — | — | |
| SCHEMBL7551937 | 0.76 | — | — | |
| SCHEMBL6283994 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1042 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979955-B | Preparation method of heterocyclic ester compound | 河南农业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-116411037-A | Preparation method of azacyclic ester compound | 河南农业大学 | 2023-07-11 | — | — | CN | claimed |
| CN-113979955-A | Preparation method of heterocyclic ester compound | 河南农业大学 | 2022-01-28 | — | — | CN | claimed |
| CN-108440523-A | A kind of new method of synthesis bromo- 3,4- dihydros -1H- [1,8] naphthyridines -2- ketone of 6- | 爱斯特（成都）生物制药股份有限公司 | 2018-08-24 | — | — | CN | claimed |
| US-9242974-B2 | Processes for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2016-01-26 | — | — | US | claimed |
| EP-2046804-B1 | Synthesis of diethyl{[5-(3-fluorophenyl)-pyridine-2-yl]methyl} phosphonate used in the synthesis of himbacine analogs | MERCK SHARP & DOHME (US) | 2015-07-15 | — | — | EP | claimed |
| US-20140073797-A1 | PROCESSES FOR THE PREPARATION OF 2-FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | claimed |
| CN-101511852-B | Synthesis of diethyl { [5'' (3-fluorophenyl) -pyridin-2-yl ] methyl } phosphonate used in the synthesis of Himbacine analogs | SCHERING CORPORTAION | 2012-10-03 | — | — | CN | claimed |
| WO-2009137787-A1 | PROCESSES FOR THE PREPARATION OF 2-FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | claimed |
| US-20090281293-A1 | PROCESSES FOR THE PREPARATION OF 2 FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-11-12 | — | — | US | claimed |
| US-12637468-B2 | Substituted [1,2,4]triazolo[4,3-b]pyridazines as GABAA receptor modulators | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2026-05-26 | — | — | US | disclosed |
| EP-4745134-A1 | PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| EP-4073062-B1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | RYVU THERAPEUTICS S A (PL) | 2026-04-29 | — | — | EP | disclosed |
| US-12612407-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist | BEONE MEDICINES I GMBH (CH) | 2026-04-28 | — | — | US | disclosed |
| US-20260085056-A1 | OX1 RECEPTOR ANTAGONISTS | NXERA PHARMA UK LIMITED (GB) | 2026-03-26 | — | — | US | disclosed |
| WO-2003048164-A2 | ADENOSINE A2A RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2003-06-12 | — | — | WO | disclosed |
| US-20020058664-A1 | Beta-amino acid derivatives--inhibitors of leukocyte adhesion mediated by VLA-4 | WYETH | 2002-05-16 | — | — | US | disclosed |
| WO-2002008201-A2 | BETA-AMINO ACID DERIVATIVES-INHIBITORS OF LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-1995028400-A1 | NOVEL BENZOFUSED 5-MEMBERED HETEROCYCLIC RINGS FOR THE TREATMENT OF MIGRAINE | GLAXO GROUP LIMITED (GB) | 1995-10-26 | — | — | WO | disclosed |
| US-4332944-A | Compositions and use | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |