Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.71 |
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060055 | 0.93 | CCR1 (0.83) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5060057 | 0.93 | CCR1 (0.83) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5060054 | 0.93 | CCR1 (0.83) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5066515 | 0.92 | CCR1 (0.73) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5066509 | 0.92 | CCR1 (0.73) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5066506 | 0.92 | CCR1 (0.73) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5972312 | 0.90 | CCR1 (0.84) | CCR1FPR3GPR65GPR35 | |
| SCHEMBL4588922 | 0.90 | CCR1 (0.84) | CCR1FPR3GPR65GPR35 | |
| SCHEMBL5060948 | 0.90 | CCR1 (0.70) | CCR1FPR3GPR65GPR35MAPK13 | |
| SCHEMBL5060949 | 0.90 | CCR1 (0.70) | CCR1FPR3GPR65GPR35MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119471-A1 | Piperazine urea derivatives for the treatment of endometriosis | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-05-22 | — | — | US | claimed |
| US-20080119471-A1 | Piperazine urea derivatives for the treatment of endometriosis | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119471-A1 | Piperazine urea derivatives for the treatment of endometriosis | ESR2, GPER1, SLC14A1 | CCR1 4304/4885FPR3 4042/4885GPR65 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.