Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 3/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736047 | 1.00 | SLC7A5 (0.38) | SLC7A5SLC1A3SLC1A2RNPEPMME | |
| SCHEMBL5067944 | 1.00 | SLC7A5 (0.38) | SLC7A5SLC1A3SLC1A2RNPEPMME | |
| SCHEMBL1320492 | 0.87 | TRPA1 (0.32) | — | |
| SCHEMBL16195856 | 0.86 | — | — | |
| SCHEMBL14909646 | 0.83 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2RNPEPSLC1A1 | |
| SCHEMBL14909647 | 0.83 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2RNPEPSLC1A1 | |
| SCHEMBL1642847 | 0.80 | — | — | |
| SCHEMBL14909153 | 0.80 | — | — | |
| SCHEMBL18342420 | 0.78 | — | — | |
| SCHEMBL15413518 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318947-A1 | Inhibitors of Akt Activity | HEERDING DIRK A | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318947-A1 | Inhibitors of Akt Activity | PI4KB, PIK3CA, AKT2 | SLC7A5 3849/4885SLC1A3 4152/4885SLC1A2 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.