Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 7/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811395 | 0.85 | MAOB (0.50) | BCL2MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL810695 | 0.85 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1LMNARAF1 | |
| SCHEMBL2964633 | 0.85 | MAOB (0.52) | BCL2MAPTSMN1; SMN2LMNAMAOB | |
| SCHEMBL810159 | 0.83 | MAOB (0.50) | MAPTSMN1; SMN2ALDH1A1LMNAMAOB | |
| SCHEMBL810233 | 0.83 | SIRT2 (0.50) | MAPTSMN1; SMN2MAOBMAOA | |
| SCHEMBL810842 | 0.82 | MEN1 (0.53) | MAPTSMN1; SMN2VCAM1MAOBMAOA | |
| SCHEMBL29463873 | 0.82 | MEN1 (0.53) | MAPTSMN1; SMN2VCAM1MAOBMAOA | |
| SCHEMBL811221 | 0.82 | APP (0.49) | BCL2MCL1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL810308 | 0.80 | VCAM1 (0.61) | MAPTSMN1; SMN2VCAM1MAOBMAOA | |
| SCHEMBL810929 | 0.77 | MAOB (0.56) | MAPTLMNAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |