Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEPT1 | Q9Y6K0 | 12/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.69 |
| ▸ | CETP | P11597 | 9/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1736218 | 0.81 | CEPT1 (1.00) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1734895 | 0.80 | CEPT1 (0.84) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL4534132 | 0.80 | CETP (0.86) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1733987 | 0.80 | MAPT (1.00) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1734909 | 0.79 | CEPT1 (0.82) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1736232 | 0.79 | CEPT1 (1.00) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL13677062 | 0.79 | CETP (1.00) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1736237 | 0.79 | CETP (0.83) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1733956 | 0.79 | CETP (1.00) | CEPT1MAPTRXFP1CETPTP53 | |
| SCHEMBL1733627 | 0.79 | CEPT1 (1.00) | CEPT1MAPTRXFP1CETPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954287-A2 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007070173-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-06-21 | — | — | WO | disclosed |