SCHEMBL5065112

SCHEMBL5065112

C[Si](C)(C)NC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20838223 0.96
SCHEMBL21828788 0.77
SCHEMBL11314419 0.77 ADH1B (0.30)
SCHEMBL8764067 0.69
SCHEMBL9148234 0.69
SCHEMBL8764084 0.67
SCHEMBL8763656 0.67 ADH1B (0.36)
SCHEMBL8763216 0.67
SCHEMBL8764042 0.62 ADH1B (0.35)
SCHEMBL9187238 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549038-B Polysubstituted isobenzofuran compound and application thereof 常州大学 2023-05-23 CN claimed
CN-106463397-A Method and system to improve drying of flexible nano-structures 东京毅力科创株式会社 2017-02-22 CN claimed
US-4960809-A CURABLE MIXTURE OF ALKOXYSILYL-CONTAINING ADDITION COPOLYMER AND AN AMIDATED POLYMER OF AN AMINE-CONTAINING ALKOXYSILANE AND SILYLATING AGENT; ADHESION TO SILICONE OVERCOATINGS AND POLYCARBONATE SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-10-02 US claimed
US-20230173079-A1 Conjugate Molecules DIVERSE BIOTECH, INC. (US) 2023-06-08 US disclosed
US-20230173079-A1 Conjugate Molecules DIVERSE BIOTECH, INC. (US) 2023-06-08 US disclosed
CN-113549038-B Polysubstituted isobenzofuran compound and application thereof 常州大学 2023-05-23 CN disclosed
CN-113549038-B Polysubstituted isobenzofuran compound and application thereof 常州大学 2023-05-23 CN disclosed
CN-114685505-A Imidazopyrrolopyridines as JAK family kinase inhibitors 詹森药业有限公司 2022-07-01 CN disclosed
CN-110461791-B Broad band antireflective sol-gel coating compositions 基金技术研究与创新公司 2022-05-13 CN disclosed
CN-110312719-B Imidazopyrrolopyridines as JAK family kinase inhibitors 詹森药业有限公司 2022-04-15 CN disclosed
CN-113549038-A Polysubstituted isobenzofuran compounds and uses thereof 常州大学 2021-10-26 CN disclosed
EP-0389176-A2 Beta-lactams and processes for their preparation Beecham Group p.l.c. (GB) 1990-09-26 EP disclosed
US-4950323-A Herbicidal bis-formyl-N-aryl-N'-alkyl ureas and methods of use ICI AMERICAS INC. 1990-08-21 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed
US-4876251-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-24 US disclosed
US-4835150-A ANTIBIOTICS BEECHAM GROUP P.L.C. (GB) 1989-05-30 US disclosed
EP-0249909-A1 Tricyclic penam compounds, their production and their use Takeda Chemical Industries, Ltd. (JP) 1987-12-23 EP disclosed
US-4609749-A Method for the simultaneous preparation of carboxylic acid trimethylsilyl esters and silylated carboxylic acid amides DYNAMIT NOBEL AG (DE) 1986-09-02 US disclosed
US-4609749-A Method for the simultaneous preparation of carboxylic acid trimethylsilyl esters and silylated carboxylic acid amides DYNAMIT NOBEL AG (DE) 1986-09-02 US disclosed
US-4008198-A POLYSILOXANE WACKER-CHEMIE GMBH (DT) 1977-02-15 US disclosed